The test paper tube mainly refers to the in vitro test strip packaging container, which has strong professional characteristics and guarantees the validity of the test paper. Therefore, the sealing of the bottle body and the bottle cap has a great influence on protecting the validity period of the test strip in vitro. In addition to the sealing and moisture absorption rates, there are several points to be noted in the packaging of qualified test strips:
1. Appearance: uniform color, no damage, no oil, good cooperation
2. Desiccant moisture content: less than 4.8%.
3. anti-drop: desiccant should not spill.
4. Cardboard: The moisture content is less than 6%, there is no fluorescence reaction, and the heavy metal is less than 5 parts per million.
5. the dissolution: heavy metals, easy oxides, non-volatiles.
6. microorganisms: bacteria less than 1000, mold yeast less than 100, Escherichia coli can not be detected.
7. abnormal toxicity can not be detected.
Caps of test strips packaging play a key role - with an integrated desiccant design that helps customers reduce overall costs. The clamshell seal increases consumer appeal and is ergonomically designed to encourage consumers to close the seal and extend protection. Different types and amounts of desiccant can be customized according to customer requirements.
Tuesday, November 19, 2019
Thursday, November 14, 2019
What should you pay attention to when using the syringe?
The perfusion device is generally made of polyethylene material, and its structure is mainly composed of a sleeve, a push rod, a piston, a positioning ring and a protective cap. The perfusion device is mainly sterilized by an ethylene oxide sterilization device, and is sterile and pyrogen free. This type of syringe can be filled with liquid in advance, which is convenient and quick to operate. The veterinary drug market continues to increase its demand!
Note the following when administering with a syringe:
First, you should pay attention to whether the syringe is clean and the package is damaged before using the syringe.
Second, whether the pre-filled drug in the perfusion device is degraded, and whether the drug solution exceeds the expiration date;
Third, whether the syringe use site is disinfected after several injections before injection;
Fourth, take corresponding measures according to the situation of sick animals;
Note the following when administering with a syringe:
First, you should pay attention to whether the syringe is clean and the package is damaged before using the syringe.
Second, whether the pre-filled drug in the perfusion device is degraded, and whether the drug solution exceeds the expiration date;
Third, whether the syringe use site is disinfected after several injections before injection;
Fourth, take corresponding measures according to the situation of sick animals;
Thursday, November 7, 2019
New requirements for candy tablet packaging of health products - moisture-proof drying
The health care candy tablet refers to the health care product produced by the candy tableting process, usually generally a tablet. The purpose of the tableting process for health care products is to make the health care products tablets have a better taste and improve the user's eating experience.
At present, the candy tableting industry is gradually adopting moisture-proof dry bottles. This kind of packaging has good sealing performance and integrates desiccant into the bottle cap, which can effectively prevent the tablets from contacting the desiccant and can achieve the purpose of absorbing water molecules, so as to keep the packaging drying inside.
The health care candy tablet packaging tube cap has a small store box to store the desiccant which can prevent the candy tablet from moisture.The desiccant is on the top of the lid, and the lid is directly sealed with the tube body without the need for a gasket. The cap is made by injection molding, and the bottle body is injection-blasted. The general capacity is less than 100ml. Printing can be done according to customer requirements.
The new effervescent tablet packaging caps are designed with an integrated desiccant to help customers reduce overall costs. The clamshell seal increases consumer appeal and is ergonomically designed to encourage consumers to close the seal and extend protection.
At present, the candy tableting industry is gradually adopting moisture-proof dry bottles. This kind of packaging has good sealing performance and integrates desiccant into the bottle cap, which can effectively prevent the tablets from contacting the desiccant and can achieve the purpose of absorbing water molecules, so as to keep the packaging drying inside.
The health care candy tablet packaging tube cap has a small store box to store the desiccant which can prevent the candy tablet from moisture.The desiccant is on the top of the lid, and the lid is directly sealed with the tube body without the need for a gasket. The cap is made by injection molding, and the bottle body is injection-blasted. The general capacity is less than 100ml. Printing can be done according to customer requirements.
The new effervescent tablet packaging caps are designed with an integrated desiccant to help customers reduce overall costs. The clamshell seal increases consumer appeal and is ergonomically designed to encourage consumers to close the seal and extend protection.
Thursday, October 31, 2019
The source of moisture and the number of water molecules in effervescent tablet tube
There are several sources of moisture in effervescent tablet tube:
First, the effervescent tablet tube's body and the cap material itself have a certain amount of moisture.
Second, the evaporation of water in the medicine and packaging materials during the production process and storage.
Third, the moisture contained in the medicine itself.
Fourth, the moisture contained in the air in the packaging after the packaging container is sealed.
Fifth, after sealing, the water molecules in the external atmosphere penetrate into the product during transportation and storage.
Physically adsorbing water molecules into their structures, or chemically absorbing water molecules and changing their chemical structure to become another substance.
Influence factors of water molecules number in the effervescent tube:
1.The size of the packaging container (dry space), the humidity requirements of the packaged product (the relative humidity of the predetermined control)
2.the water content of the product itself
3. The properties of the packaging materials used in the product (especially moisture permeability)
4.the level of sealing of the product packaging
5.The temperature and humidity of the environment when the product is packaged, the shelf life of the product, the environment and climatic conditions for product transportation and storage, etc.
6.the absorbency of the desiccant
First, the effervescent tablet tube's body and the cap material itself have a certain amount of moisture.
Second, the evaporation of water in the medicine and packaging materials during the production process and storage.
Third, the moisture contained in the medicine itself.
Fourth, the moisture contained in the air in the packaging after the packaging container is sealed.
Fifth, after sealing, the water molecules in the external atmosphere penetrate into the product during transportation and storage.
Physically adsorbing water molecules into their structures, or chemically absorbing water molecules and changing their chemical structure to become another substance.
Influence factors of water molecules number in the effervescent tube:
1.The size of the packaging container (dry space), the humidity requirements of the packaged product (the relative humidity of the predetermined control)
2.the water content of the product itself
3. The properties of the packaging materials used in the product (especially moisture permeability)
4.the level of sealing of the product packaging
5.The temperature and humidity of the environment when the product is packaged, the shelf life of the product, the environment and climatic conditions for product transportation and storage, etc.
6.the absorbency of the desiccant
Thursday, October 24, 2019
Biologics packaging - COP vials
With the continuous development of biopharmaceutical technology,the COP vials are used more and more widely.
COP vials are made from a cyclic olefin polymer (COP); polymers are considered to be more stable materials than glass compared to glass. Compared with most glass bottles, COP has no protein adsorption, which can guarantee the content of active ingredients in medicines. Due to the use of polymer material properties, it has a high-end positioning in the industry compared to most vials. It is especially suitable for complex molecules and sensitive drugs that require high stability.
Thursday, October 17, 2019
What are the main factors in the storage management of veterinary medicine?
The quality of veterinary medicines includes the intrinsic quality, appearance quality and packaging quality of the drugs. The appearance quality of a drug refers to the physical and biological properties of the drug, such as color, odor, crystal or insoluble matter, morphology, solubility, weathering, deliquescence, mildew, insects and so on.
1.visual inspection: 1 inspection of packaging, containers and labels; 2 inspection of raw materials; 3 inspection of various preparations.
2. Factors affecting the deterioration of drugs:
1.visual inspection: 1 inspection of packaging, containers and labels; 2 inspection of raw materials; 3 inspection of various preparations.
2. Factors affecting the deterioration of drugs:
- Air: The oxygen in the air can cause many of the reducing agents to oxidize and produce toxicity, such as oil rancidity; carbon dioxide in the air makes the sulfa drug carbonate.
- Light: Ultraviolet rays can cause many drugs to undergo chemical reactions such as discoloration, oxidation, reduction and decomposition. For example, silver nitrate and mercury are photosynthetically reduced to precipitate dark brown toxic silver and mercury.
- Temperature: The increase of temperature can accelerate the volatility of the drug, and more importantly, it can promote chemical reactions such as oxidation and decomposition to accelerate the deterioration of the drug. For example, serum, vaccine and organ preparations are easy to be stored at room temperature, and need to be refrigerated at low temperature; The increase in temperature also tends to soften the ointment and capsules, and accelerate the volatilization of volatile drugs. However, if the temperature is too low, some drugs or preparations will be used to precipitate. For example, formaldehyde will form a polymeric precipitate under 9 ° C to precipitate a white precipitate; low temperature will also cause the liquid drug to freeze, causing the container to rupture.
- Humidity: The water vapor content in the air is called humidity. Humidity is the most variable part of the air and fluctuates with the region, season and temperature. Humidity has a great impact on drug storage. If the humidity is too large, the drug can absorb moisture and deliquesce, dilute, deform, and mold; the humidity is too small, and the drug containing crystal water is easily weathered (loss of crystal water).
- Microorganisms and insects: When drugs are exposed to the air, they are metabolized by microorganisms and insects, causing deterioration, fermentation, mildew and insects.
- Time: Any medicine that has been stored for too long will deteriorate, but different medicines will change at different speeds. Antibiotics, biological agents, organ preparations and certain chemicals are all valid and must be used within the validity period.
Friday, September 20, 2019
Pets feeding syringe sealability factor
The three influencing factors of pets feeding syringe are barrier properties, sealing methods, and density of feeders. These points will have a certain impact on the sealing effect of the pets feeding syringe.
1. Barrier performance of pet feeding syringe:
The barrier criteria are mainly the O2 transmittance and the water vapor transmission rate of the material. The barrier properties of the substrate will directly affect the quality of the drug during the shelf life, and it is also an important indicator for assessing the shelf life of the drug.
2. Sealing method
There are three main types of sealing methods:
The first is to seal the outer thread of the bottle with the inner thread of the bottle cap;
The second is to use the flat pressure seal, with the capping of the bottle cap, the surface of the bottle mouth and the inside of the bottle cap The gasket is contacted to achieve the sealing;
The third is the cap sealing. During the capping process, the cap with the inverted cone or the elliptical body plug is pressed into the interior of the bottle mouth, relying on the interference between the inner plug and the inner diameter of the bottle mouth. Cooperate to achieve sealing. Which sealing method is used depends mainly on the nature of the contents of the bottle.
3. The density of the pets feeding syringe
The density of pet feeders is closely related to their barrier properties and mechanical properties, and is an important basic parameter affecting the physical properties of materials. By comparing the test results of three common substrates of PP, HDPE and PET, the density of all three substrates is within the national standard.
1. Barrier performance of pet feeding syringe:
The barrier criteria are mainly the O2 transmittance and the water vapor transmission rate of the material. The barrier properties of the substrate will directly affect the quality of the drug during the shelf life, and it is also an important indicator for assessing the shelf life of the drug.
2. Sealing method
There are three main types of sealing methods:
The first is to seal the outer thread of the bottle with the inner thread of the bottle cap;
The second is to use the flat pressure seal, with the capping of the bottle cap, the surface of the bottle mouth and the inside of the bottle cap The gasket is contacted to achieve the sealing;
The third is the cap sealing. During the capping process, the cap with the inverted cone or the elliptical body plug is pressed into the interior of the bottle mouth, relying on the interference between the inner plug and the inner diameter of the bottle mouth. Cooperate to achieve sealing. Which sealing method is used depends mainly on the nature of the contents of the bottle.
3. The density of the pets feeding syringe
The density of pet feeders is closely related to their barrier properties and mechanical properties, and is an important basic parameter affecting the physical properties of materials. By comparing the test results of three common substrates of PP, HDPE and PET, the density of all three substrates is within the national standard.
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