The importance of effervescent packaging

 The main design of the effervescent tablet tube is the packaging of the effervescent tablet, which is moisture-proof and anti-damage. When the effervescent tablet is packaged early, it is the most prominent dryness of the package. There is a spiral spring to prevent the effervescence from being damaged during transportation.

effervescent tubes

Precautions for the production and pharmaceutical packaging of effervescent tablets:

1. Do not make the acid and alkali together with the main drug during granulation, because the general acid or alkali will affect the stability of the drug and may lead to unqualified degradation products.

2. The disintegration degree is not more than 5 minutes according to the pharmacopoeia, which is relatively easy to achieve. Our internal control standard is 90 seconds. When granulating, use a binder with a low viscosity and use a high concentration of ethanol to granulate (such as absolute ethanol), so that it dries quickly, the particles are relatively loose, and the degree of disintegration is easily qualified. But pay attention to the friability, the pharmacopoeia stipulates no more than 1%. (But it seems that a special application can be made for effervescent tablets, which should be relaxed appropriately.) Finally, acid and alkali are added as additional auxiliary materials in the final mixing.

3. Be careful not to store the prepared pellets for too long, and control the humidity.

4. The humidity should also be controlled during tablet pressing to prevent water absorption.

5. As for packaging, you can choose double aluminum packaging or high-density polyethylene bottle or PP plastic bottle packaging that is not easily permeable to water and oxygen to ensure its stability.

Effervescent Tablet Tube

The concept of the inspection result exceeding standard management was introduced for the first time, which means that the test result is beyond the legal standard and the enterprise internal control standard. Excessive inspection results do not necessarily mean that the sample inspection is not qualified. How can the effervescent tablet tube manufacturer be implemented?

effervescent packaging

First, the operating procedures for the establishment of inspection results exceeding the limits of the investigation within the company. Laboratory investigation was carried out according to the regulations to confirm whether it was laboratory bias. If it is not the laboratory deviation, the R & D, technology and production personnel should be organized to investigate the production process. It can also be interpreted as two categories: laboratory bias and non laboratory bias.

effervescent tablet tube

The laboratory deviation shall investigate any deviation of the test results caused by the factors related to the inspection process,A laboratory survey should be carried out by the professional personnel. The non laboratory deviation refers to the deviation of the test results caused by any other factors except the deviation of the laboratory. The above deviation analysis also standardizes the concrete implementation of the inspection results exceeding the standard for effervescent tablet tube factory. 

The source of moisture and the number of water molecules in effervescent tablet tube

There are several sources of moisture in effervescent tablet tube：
First, the effervescent tablet tube's body and the cap material itself have a certain amount of moisture.
Second, the evaporation of water in the medicine and packaging materials during the production process and storage.
Third, the moisture contained in the medicine itself.
Fourth, the moisture contained in the air in the packaging after the packaging container is sealed.
Fifth, after sealing, the water molecules in the external atmosphere penetrate into the product during transportation and storage.
Physically adsorbing water molecules into their structures, or chemically absorbing water molecules and changing their chemical structure to become another substance.
Influence factors of water molecules number in the effervescent tube:
1.The size of the packaging container (dry space), the humidity requirements of the packaged product (the relative humidity of the predetermined control)
2.the water content of the product itself
3. The properties of the packaging materials used in the product (especially moisture permeability)
4.the level of sealing of the product packaging
5.The temperature and humidity of the environment when the product is packaged, the shelf life of the product, the environment and climatic conditions for product transportation and storage, etc.
6.the absorbency of the desiccant

The structure of effervescent tablet tube's desiccant cap

The effervescent tablet tube's desiccant cap serves as a container for protecting medicines from moisture or damage to medicines, health foods and diagnostic products. The bottle body and cap form a sealing system to prevent sensitive products from getting wet, prolong the shelf life and enhance brand value. The moisture-proof combination bottle body and cap use special design features and plastic materials to prevent moisture from entering and absorb moisture generated by water vapor transmission effect. The moisture-proof combination cover features include:
1. Anti-theft ring: There is no bottle buckle at the bottle neck. When the moisture-proof cover is covered, the anti-theft ring will be stuck. When it is opened, the anti-theft ring will automatically fall off.
2. Sealing: It adopts double material system (polyethylene cap and polypropylene bottle body) and innovative shaping design. The sealing and container are perfectly sealed, and the water vapor transmission effect is strictly controlled.
3, cork spring: optional cap to ensure that the tablet does not shift, especially during transportation, to avoid the bumps affected by the bumps
4, desiccant: the desiccant chamber of the bottle cap can be used to match the desiccant of various types, quantities and attributes to ensure that the product is properly protected.

Effervescent Tablet Tube Test

The concept of the inspection result exceeding standard management was introduced for the first time, which means that the test result is beyond the legal standard and the enterprise internal control standard. Excessive inspection results do not necessarily mean that the sample inspection is not qualified. How can the effervescent tablet tube manufacturer be implemented?

First, the operating procedures for the establishment of inspection results exceeding the limits of the investigation within the company. Laboratory investigation was carried out according to the regulations to confirm whether it was laboratory bias. If it is not the laboratory deviation, the R & D, technology and production personnel should be organized to investigate the production process. It can also be interpreted as two categories: laboratory bias and non laboratory bias.

The laboratory deviation shall investigate any deviation of the test results caused by the factors related to the inspection process,A laboratory survey should be carried out by the professional personnel. The non laboratory deviation refers to the deviation of the test results caused by any other factors except the deviation of the laboratory. The above deviation analysis also standardizes the concrete implementation of the inspection results exceeding the standard for effervescent tablet tube factory.

The desiccant packaging of effervescent tablet

It is well known for people that the effervescent tablet can react with water,so when you store the effervescent table, you need avoid the moisture of air.And the effervescent tablet tube can ensures optimal performance of effervescent tablets, effervescent packaging consists of one-piece, flip-top desiccated vials, and desiccated bottles across a range of sizes.

Effervescent tablets packaging adopts plastic tube and desiccant caps to achieve moisture protection, this design is conventient for customers to carry anywhere, the tube diamater is suitable for effervescent tablets or supplements, the length can be suitable for 10pcs, 20pcs tablets, of course we can slao offer customization for your products. Desiccant cap according to user-friendly design, there are small hand pattern on the top of the cap, which can make users know how to open the cap easily, there is also has open design for hands. There are desiccant container and spring ring inside the cap, desiccant including silica and molecular sieve, which can keep the tube in dry environment, while spring ring can prevent the tablets damaging during the transport.

The Standard of Effervescent Tablet Tube Desiccant Cap

The desiccant cap of effervescent tablet tube is made of LDPE raw material, which is mainly used in the plastic oral solid pharmaceutical container, also including silica gel, molecular sieve or hybrid desiccant (Silicone: large molecular sieve 4:6), With cardboard as the block material effervescent tablet bottle moisture combination cap.

                                         moisture proof tamper container
Surface
The bottle color and gloss is uniform appearance, can not have clear off color.The cover surface should be smooth, level off, can not have deformation and obvious scratch.Can not have sand holes, oil, air bubbles. Defense right connection bridge without damage. Dialysis cardboard surface with no dirt, should level off, and cap with appropriate;Desiccant color and gloss is normal, no dirty.
Distinguish
Infrared Spectrum
To effervescent tablet tube desiccant cap amount.According to the packing material infrared spectrometric method for the first method or the fourth method, it shall conform to the basic control map.

                                                      desiccant closure
Sealing
Take cover 2.0 g, inspection in accordance with the law of the People's Republic of China (pharmacopeia 2000 edition of the appendix) legacy residuals shall not be over 0.1%.
Xinfuda effervescent tablet tube desiccant cap meet the standard of effervescent tablet tube desiccant cap.

vitamin&chew tablet's effervescent tablet container

Effervescent tablet container is made of moisture proof tamper closure and effervescent tablet tube, which with injection molding process of production. Effervescent vitamin tablet and chew has a higher requirement for food packaging. Ordinary tablet can not has obvious effects compared with effervescent tablets, effervescent tablet need dry environment for a long expiration date.
Effervescent tablets container marked characteristics: Anti-fake label-unique way of printing, to completely eliminate the use of labeling fraud, ensure the company's interests and reputation, reduce company cost impact.
Safety-install the desiccant in effervescent tablet bottle lid, put an end to eating, misuse, and to ensure the safety of users.
Advertising - color printing packaging for colorful, the label color is more bright-coloured, rubbing. Virtually raised the enterprise products, enterprise strength, good advertising effect.
Save money - for enterprises to reduce equipment investment, reduce the labor, save energy more than 70%.

Desiccant cap for effervescent tablet bottle

If the effervescent tablet tube don’t open the packaging, The desiccant cap experimental theory data is two years. However it is used for 12-18 month in practical application. Two main desiccant are silica and molecular, and silica is the only one met demands of FDA. Desiccant cap and effervescent tablet container make the vitamin and  chew healthy and dry.

                                                moisture proof tamper closure
Silica of desiccant cap is a highly active adsorption material, It is hard, non-toxic, tasteless, non-corrosive, also strong chemical stability and thermal stability.

                                                             desiccant cap
Silica has strong hydrophilia, at the same time has many holes with out eyes seeing on the surface of the silica gel desiccant cap, make its surface area has greatly increased, these characteristics of silica gel desiccant decided to become a good hygroscopicity of desiccant.

Xinfuda will share the plastic pharmaceutical bottle in API exhibition

The API exhibition is one of the professional medical exhibition.

We will attend the API exhibition which will be hold in shanghai on April 11-April 14.Welcome the people who is working in medicine.We will waiting for you.

The pharmaceutical bottle will share in API

These days,we will share our classical bottles and new design bottles.For example,veterinary paste syringe,effervescent tablet tube,twin neck bottle,vaccine bottle,child proof bottle and so on.We also can design products according your need.Our goal is that developping effective solutions with customized service for client.

what do your company manufacture?

Oh,I will introduce my company.My company which is named Xinfuda is a pharmaceutical packaging group which is from China,Xinfuda owns factory which meet the GMP Standard.Our factory has the whole bottle product line which has many machines that are imported overseas.

The Workshop of inject plastic bottle

you do not know the secret about the closure of effervescent vitamin C tablets

the closure of effervescent vitamin C tablets

you do not know the secret about the closure of effervescent vitamin C tablets

Usually we often drink vitamin C tablets to get vitamin supplement, and i wonder that whether you are curious about why the tablets is always dry? Whether you observe the cap of the tubes?

Let me expose a secret, of course, i guess all of you may have guessed it. It must be influenced on the tablets packaging. Watch the packaging carefully, you will find that the closure of the effervescent vitamin tablets is special, usually there is a store on the top of cover, so are you curious what is inside of the store?
There are silica gel desiccant in the store, as is well know that in order to keep the food or medicine effectiveness we need some desiccant. However only silica gel desiccant is meet the FDA food standard. Silica gel desiccant can absorb water to offer tablets a dry enviroment, another is that desicccant in the store will not touch the tablets directly, which is beter than desiccant in bags.

silica gel closure

So packaging is a magical angel for medicine and food, which offer health for people, packaging is also functional.

How Can Silica-gel Desiccant of Plastic Vitamin Tube Keep Dry?

Plastic vitamin tube is used in vitamin tablet packaging due to its dry environment. There are silical-gel desiccant and large molecular sieve desiccant in plastic vatimin tube. However, silica-gel desiccant is the only one through FDA and healthy for human.

 

desiccant closure

Silica-gel desiccant in vitamin tube is a highly active adsorbent material, which belongs to amorphous material. Silic-gel desiccant of vitamin tube cap insoluble in water, non-toxic and tasteless, chemically stable. According to diameter, silica can be divided into macroporous silica gel, coarse - hole silica gel, type B silicone, fine - hole silica gel. Silica can reuse through rebirth. The main ingredient of silica-gel desiccant is Sio2, for more translucent amorphous, composed of natural mineral processed granular or bead, usually after treatment with sulfuric acid to form, its hard, non-toxic, tasteless, non-corrosive, good chemical stability and thermal stability.

plastic vitamin tube

  

Silica-gel desiccant of vitamin tube covers many hydroxyl groups with strong hydrophilicity, at the same time, the surface of silica gel desiccant has many small holes that are not visible to the naked eye, so that its surface area is greatly increased, and the properties of silica gel desiccant decide to become a good desiccant.Desiccant moisture environment as temperature of the shelf life is most suitable for 20 ~ 32 ℃.

Xinfuda as a China major effervescent packaging manufacturer with DMF, which can offer excellent desiccant packaging for vitamin tablets. Plastic vitamin tube adopted silica-gel desiccant to keep dry and the spring on the cap can prevent tablets damaging.

What Should You Pay Attention on Choosing Vitamin C Tube?

Vitamin C tube belongs to a special packaging in the international, which has strong professionalism. The sealed fitting of bottle body and cap is important for avoiding vitamin C tablets wetting. It is the key step for vitamin C tablet manufacturerto choose suitable packaging.Except sealing, there are also some points need to pay attention.

effervescent tablet  tube

First, surface: Color uniform, no damage, no oil, good match.

Second, the moisture content of the drying agent:lower than 4.8%.

Third, anti-fall: desiccant must not be dropped

Fourth, board: moisture content below 6%, no fluorescence reaction, heavy metal less than 5 parts per million.

Fifth, dissolution: heavy metals, oxides and non-volatile substances.

Sixth, microorganisms: bacteria less than 1000, mould yeast less than 100, escherichia coli may not be detected.

Seventh, abnormal toxicity should not be detected.

144mm effervescent tablet packaging 

Vitamin C tube has an important part is that spiral desiccant cap, spiral desiccant cap is the international univerisal cap for effervescent tablets, the structure has high requirement for mould design, even some countries can not volum production. The spiral in the cap can buffer the impact of the transport process, thus protecting fragile effervescent tablets will not be damaged.

The selection of high-quality vitamin C tube will also need to analyze the strength, equipment and comprehensive quality of the manufacturers, and the high quality of the enterprise products will be stable, which will help your products to be more smooth in the competition.

China Plastic Tube with Desiccant Cap Supplier

China plastic tube with cap can be produced by Xinfuda Medical Packaging manufacturer, plastic tube with cap is usually used in effervescent tablet and test strip.

China plastic tube with cap

Plastic tube with cap is made of different sizes tube and desiccant cap with spiral, which can be more safe for tablets, there are five sizes including 84mm, 99mm, 96mm, 133mm and 144mm. 

Xinfuda will attend Supply Side West on 27th September 2017

Xinfuda will attend the exhibition of SSW in Las Vegas from 27^th to 28^th September 2017, as a China pharmaceutical packaging manufacturer, there are desiccant bottle, effervescent tablet tube and child resistant cap. Welcome friends coming to our booth No.:N179.

Xinfuda in supply side west

SupplySide West brings together more than 15,000 ingredient buyers and suppliers from the dietary supplement, beverage, functional food, personal care and sports nutrition industries. SupplySide West is all about the science and strategy around the development of finished products that drive the global business economy. Join us this year to learn about new trends from over 1,200 exhibitors and 140 hours of educational and conference programming.  

China Plastic Tube with Desiccant Cap Supplier

China plastic tube with cap can be produced by Xinfuda Medical Packaging manufacturer, plastic tube with cap is usually used in effervescent tablet tube and test strip.

effervescent tablet packaging

Plastic tube with cap is made of different sizes tube and desiccant cap with spiral, which can be more safe for tablets, there are five sizes including 84mm, 99mm, 96mm, 133mm and 144mm. 

Effervescent tablet tube for vitamin and chew China Plastic supplier&factory

 Moisture proof composite cover is Manufactured by Injection Molding Process. Mainly use the LDPE raw material, built-in desiccant or molecular sieve for moisture proof, that can make sure inside tablets no affected with damp. Spiral fixed spring compaction cap prevents tablets waggle and abrasion.

Moisture Proof Tampers and caps

Effervescent tablet tube Features:

1, Anti-Fake: Unique Printing Way can completely eradicate using the labeling to counterfeit, that will Protect the interests and reputation of company, reduce the cost of cracking down on fake products.

2, Safety: Install the desiccant in the lid, completely eradicate wrong eating and wrong using, to ensure the safety of users

3, Advertisements: Color printing packaging, lebel color is more bright-coloured, rub resistant, smooth Hand feeling, virtually increased grade of the products, enterprise strength, have a good advertising effect

4, Save your money: Reduce equipment investment, reduce the labor, and Save energy of more than 70%

5, Help you to create your own brand, strengthen brand.

Effervescent tablet tube manufacturer with desiccant closure

  Effervescent tablet tube as an important packaging for vitamin and chew in effervescent packaging, due to its excellent sealing and desiccant. Xinfuda effervescent tablet tube sizes from 84mm to 144mm with moisture proof tamper closure. The desiccant cap with spring can prevent the tablet shaking.

  The cap of effervescent tablet tube takes the important impact on the food or medicine. The tube can be used for vitamin, chew, test strip and so on. Test strip packaging also as a popular packaging in lab test equipment.

           

  Effervescent tablet tube is made of PP raw material, which has high hardness, acid and alkali corrosion, high . However its flexibility is lower than PE. Effervescent tablet tube with moisture proof tamper perform well in storing capsules and tablets which need dry condition.

effervescent tablet tube manufacturer

   
     Effervescent tablet tube as an important packaging for vitamin and chew, due to its excellent sealing and desiccant. Xinfuda effervescent tablet tube sizes from 84mm to 144mm with moisture proof tamper closure. The desiccant cap with spring can prevent the tablet shaking.

     The cap of effervescent tablet tube takes the important impact on the food or medicine. The tube can be used for vitamin, chew, test strip and so on. Test strip tube also as a popular packaging in lab test equipment.

     Effervescent tablet tube is made of PP raw material, which has high hardness, acid and alkali corrosion, high . However its flexibility is lower than PE. Effervescent tablet tube with moisture proof tamper perform well in storing capsules and tablets which need dry condition.

Xinfuda Pharmaceutical&Veterinary Packaging

      

     Xinfuda Medical Packaging Co., Ltd founded in 2001, specializes in designing, manufacturing and exporting a wide range of ready-made & custom-made plastic packaging products for pharmaceutical and veterinary packaging. With standard grade 10000 modern purification workshop and state-of-the-art production facilities & inspection equipments imported from Germany, such as numerically-controlled injection molding machine and blow molding machine, we have developed acknowledged quality plastic (PE, PP, PET etc.) bottles and containers with different capacities (from 5ml to 6000ml), shapes, colors and caps for domestic and oversea clients.

     Our current products include oral paste syringe, effervescent tablet tube, healthcare container, Moisture proof container, PET bottle, Vaccine injection vial&bottle, plastic liquid bottle, twin neck bottle, COP injection vial, Oral dry powder inhaler. With its fixed assets USD90,000,000, Xinfuda located its headquarter at Zhaoxian Industrial Part, Shijiazhuang city. At present, there are 2 factories covering an area of more than 60,000 square meters. To date, we have the capability to manufacture in excess of 3,000,000 bottles & containers per week. As a professional leading production enterprise in North China, Xinfuda has passed ISO 9001:2008 International Quality Management System Certification. Whilst it received the Registration License of Drug Packaging Materials and Containers awarded by the State Food and Drug Administration, as well as the Standing Director Member of China Veterinary Drugs Association, China Pharmaceutical Packaging Association and China Alliance of Green Industry.