how to choose the desiccant for pharmaceutical packaging

 

caps with silica for effervescent tablet tubes

How to choose the desiccant like silica gel or molecular sieve for pharmaceutical packaging.

No matter you choose silica gel or molecular sieve,the first step is that confirm the dosage of the desiccant which you will use in the effervescent tube. You need confirm the size of effervescent tube,then according to the size,confirm the dosage of the desiccant.In generally,the dosage of effervescent tube is 2.1g and 3.9g. 

Then you need research your target market,your target market whether permit use molecular sieve,because some countries don't permit use molecular sieve, the temperature of storing environment can influence the moisture absorption ability of silica gel and molecular sieve.The most suitable temperature of silica gel is 20~32°C and 60~90°C.

Structural principles of cap sealing requirements

 The sealing performance of the pharmaceutical plastic bottle cap is generally said to be the sealing performance of the bottle mouth and the cap. The cap has a good sealing performance to prevent leakage of gas and liquid inside the bottle.

caps manufacturer

There are three areas for the cap to provide sealing ability, which are the inner cap of the cap, the outer cap of the cap, and the cap of the cap. Each sealing area has a certain amount of deformation with the mouth of the bottle. This deformation amount constantly applies a certain force to the mouth of the bottle to produce a sealing effect. Not all caps are sealed by three seals, and most caps are used. The inner seal and the outer seal can be used.

For plastic bottle manufacturers, the cap sealing performance is a project that needs continuous monitoring, that is, the sealing performance needs to be checked regularly. Perhaps many small-scale cap factories do not pay much attention to the cap sealing test. Some people may use the original simple method to test the tightness. For example, after sealing the cap, use hand squeeze and foot to check the tightness.

Xinfuda offer child resistant cap, desiccant caps, sprial desiccant caps, common caps

Effervescent Packaging China Manufacturer

Xinfuda group can offer customers what you need in pharmaceutical packaging area. Xinfuda as the pioneer pharmaceutical packaging manufacture in northern China. High quality, strong supply capacity and shorten shipping cycle can meet your all demand. Effervescent packaging is one set in our products.

effervescent packaging

Effervescent packaging has two series which are effervescent tablets tubes and test strip tube. The main is that desiccant cap, which can perform well in storing capsules and tablets that need dry condition. Of course, we also introduce the desiccant shelf, component of effervescent packaging and characteristics of effervescent tablets bottles. Effervescent packaging has five sizes include 84mm, 96mm, 99mm, 133mm, 144mm.

sprial desiccant cap

These can give you more choose to match your products. The raw material is PP. All the products meet the DMF and produce in CGMP standard. We will be your reliable partners in packaging.

Desiccant cap production process

As a component of medicinal plastic bottles in pharmaceutical packaging, the production and processing of desiccant caps are similar to the requirements of the bottle body, except that the main raw material of the bottle body is blow molding grade, while the main raw material of the bottle cap is injection molding grade.

desiccant cap

The pharmaceutical bottle cap production process is:

First, feeding and batching are mainly conveyed to the hopper of the injection molding machine through pipes. After the machine is turned on, the material in the hopper enters the person's barrel to complete the process of feeding the machine.

Secondly, plasticization is a process in which the plastic batch material that enters the barrel from the hopper is heated in the barrel to reach a flowing state and has good plasticity. The requirement is that the plastic reaches the specified molding temperature before entering the mold cavity, and a sufficient amount of molten plastic is provided within the specified time.

Third, the first injection is to inject the well-plasticized melt into the mold under the pressure of the screw (injection process). When the melt is injected into the mold cavity, it passes through the nozzle, the main (sub) runner, and the gate. The resistance is very high. It has a large injection pressure loss of 30% -70%, so the process requires a sufficient injection pressure to ensure complete mold filling. This is followed by the molding stage, which consists of four steps: disposable mold, compaction, reverse flow and gate curing. The plastic melt injected into the mold cavity is cooled and shaped into a plastic cover.

Fourth, cooling and demoulding. Mainly refers to the stage from when the plastic in the gate is completely frozen to when the lid is released from the mold. Demoulding can be divided into two types: strong demolding and spin-off.

It is necessary to grasp the various production links and avoid problems before they can produce medicinal bottle caps that the customers of high quality can trust.

The structure of effervescent tablet tube's desiccant cap

The effervescent tablet tube's desiccant cap serves as a container for protecting medicines from moisture or damage to medicines, health foods and diagnostic products. The bottle body and cap form a sealing system to prevent sensitive products from getting wet, prolong the shelf life and enhance brand value. The moisture-proof combination bottle body and cap use special design features and plastic materials to prevent moisture from entering and absorb moisture generated by water vapor transmission effect. The moisture-proof combination cover features include:
1. Anti-theft ring: There is no bottle buckle at the bottle neck. When the moisture-proof cover is covered, the anti-theft ring will be stuck. When it is opened, the anti-theft ring will automatically fall off.
2. Sealing: It adopts double material system (polyethylene cap and polypropylene bottle body) and innovative shaping design. The sealing and container are perfectly sealed, and the water vapor transmission effect is strictly controlled.
3, cork spring: optional cap to ensure that the tablet does not shift, especially during transportation, to avoid the bumps affected by the bumps
4, desiccant: the desiccant chamber of the bottle cap can be used to match the desiccant of various types, quantities and attributes to ensure that the product is properly protected.

Spiral Desiccant Closures

Spiral desiccant closures is a new design for medicine and health care container, which can keep tablets and capsules dry and safe. Spiral desiccant closures mainly used in effervescent tube and some plastic medicine bottle.

                                                           desiccant cap
Spiral desiccant closure made of silica gel, store and spiral. Silica gel can absorb water and keep the bottle dry. Store can store desiccant. Spiral can prevent tablets and capsules damage.

                                                  spiral desiccant closure
Moisture proof tamper cap divided into spiral desiccant closure and CRC.

Desiccant cap for effervescent tablet bottle

If the effervescent tablet tube don’t open the packaging, The desiccant cap experimental theory data is two years. However it is used for 12-18 month in practical application. Two main desiccant are silica and molecular, and silica is the only one met demands of FDA. Desiccant cap and effervescent tablet container make the vitamin and  chew healthy and dry.

                                                moisture proof tamper closure
Silica of desiccant cap is a highly active adsorption material, It is hard, non-toxic, tasteless, non-corrosive, also strong chemical stability and thermal stability.

                                                             desiccant cap
Silica has strong hydrophilia, at the same time has many holes with out eyes seeing on the surface of the silica gel desiccant cap, make its surface area has greatly increased, these characteristics of silica gel desiccant decided to become a good hygroscopicity of desiccant.

How to protect pharmaceuticals against moisture and oxygen?

There are multiple ways for moisture and oxygen to enter the inside of a plastic pharmaceutical bottle which can cause a drug to lose its efficiency before the end of its shelf life.So an effective way and packaging is important for medicine. Xinfuda offer the solution including silica gel and molecular sieve desiccant, as well as barrier bottles and oxygen scavengers enable the control of conditions inside drug packages.

desiccant polymers caps aganist moisture and oxygen

Moisture and oxygen can affect the chemical or physical stability of pharmaceutical products. Due to moisture vapor transmission, tablets and capsules are exposed to moisture and oxygen that can permeate the package from the outside environment. Sensitive healthcare products often need active protection to adsorb these elements to ensure optimal shelf life.

spiral desiccant closures

Xinfuda mainly adopts closures with desiccant polymers to address special packaging needs.

How Can Plastic Vitamin Tube Keep Dry Environment

Plastic vitamin tube is used in vitamin tablet packaging due to its dry environment. There are silical-gel desiccant and large molecular sieve desiccant in plastic vatimin tube. However, silica-gel desiccant is the only one through FDA and healthy for human.

desiccant cap

Silica-gel desiccant in plastic vitamin tube is a highly active adsorbent material, which belongs to amorphous material. Silic-gel desiccant of vitamin tube cap insoluble in water, non-toxic and tasteless, chemically stable. According to diameter, silica can be divided into macroporous silica gel, coarse - hole silica gel, type B silicone, fine - hole silica gel. Silica can reuse through rebirth. The main ingredient of silica-gel desiccant is Sio2, for more translucent amorphous, composed of natural mineral processed granular or bead, usually after treatment with sulfuric acid to form, its hard, non-toxic, tasteless, non-corrosive, good chemical stability and thermal stability.

plastic vitamin C tube

Silica-gel desiccant of plastic vitamin tube covers many hydroxyl groups with strong hydrophilicity, at the same time, the surface of silica gel desiccant has many small holes that are not visible to the naked eye, so that its surface area is greatly increased, and the properties of silica gel desiccant decide to become a good desiccant.Desiccant moisture environment as temperature of the shelf life is most suitable for 20 ~ 32 ℃, humidity was 60% ~ 60%, it can reduce the environmental relative humidity to 40%.

Xinfuda as a China major effervescent packaging manufacturer with DMF, which can offer excellent desiccant packaging for vitamin tablets. Plastic vitamin tube adopted silica-gel desiccant to keep dry and the spring on the cap can prevent tablets damaging.

The producing process of effervescent tablet tube

Effervescent tablet tube process manufacturer

desiccant cap process

desiccant closure

effervescent tablet tube

Effervescent tablet tube for vitamin and chew China Plastic supplier&factory

 Moisture proof composite cover is Manufactured by Injection Molding Process. Mainly use the LDPE raw material, built-in desiccant or molecular sieve for moisture proof, that can make sure inside tablets no affected with damp. Spiral fixed spring compaction cap prevents tablets waggle and abrasion.

Moisture Proof Tampers and caps

Effervescent tablet tube Features:

1, Anti-Fake: Unique Printing Way can completely eradicate using the labeling to counterfeit, that will Protect the interests and reputation of company, reduce the cost of cracking down on fake products.

2, Safety: Install the desiccant in the lid, completely eradicate wrong eating and wrong using, to ensure the safety of users

3, Advertisements: Color printing packaging, lebel color is more bright-coloured, rub resistant, smooth Hand feeling, virtually increased grade of the products, enterprise strength, have a good advertising effect

4, Save your money: Reduce equipment investment, reduce the labor, and Save energy of more than 70%

5, Help you to create your own brand, strengthen brand.

Effervescent tablet tube manufacturer with desiccant closure

  Effervescent tablet tube as an important packaging for vitamin and chew in effervescent packaging, due to its excellent sealing and desiccant. Xinfuda effervescent tablet tube sizes from 84mm to 144mm with moisture proof tamper closure. The desiccant cap with spring can prevent the tablet shaking.

  The cap of effervescent tablet tube takes the important impact on the food or medicine. The tube can be used for vitamin, chew, test strip and so on. Test strip packaging also as a popular packaging in lab test equipment.

           

  Effervescent tablet tube is made of PP raw material, which has high hardness, acid and alkali corrosion, high . However its flexibility is lower than PE. Effervescent tablet tube with moisture proof tamper perform well in storing capsules and tablets which need dry condition.