Do you understand these three characteristics of plastic veterinary paste syringes?

The plastic veterinary paste syringe is a new type of pharmaceutical packaging container with high technical content, and suitable for injection and injection.Mainly used for the treatment of cow mastitis, and creamy medicine.The paste injector is to directly inject the injected medicine into the syringe, and the syringe and the medical liquid packaging container are combined into one, and the injection is directly used, which is very convenient.Plastic veterinary paste syringes have the following outstanding features:
1. The dosage is more accurate. There are more residual liquids during use, and the plastic syringe can minimize the residual of the liquid, and the dosage is more accurate.
2. Direct injection, to avoid the staff to cause harm to themselves during the dispensing process.
3. Easy to use, no pollution: When pre-filled liquid is used, only the needle cap needs to be taken off, directly injected, no cross-contamination, and the air is not exposed to the medicine, so that the safe injection is achieved.
The plastic veterinary paste syringe produced by the animal health company can be used directly, which solves this problem well. A dose of the drug has been included in each plastic syringe and can be discarded directly after use, avoiding the potential contamination of the drug into the syringe during regular injections.

plastic veterinary paste syringe

How is the pet feeding syringe sterilized?

With the continuous development of the pet industry, the pet feeding syringe has also been continuously improved.The pet feeding syringe has a simple structure, which is mainly composed of syringe barrel, plunger, tip cap and piston.The plunger can print a scale, which can effectively ensure feeding.

The aseptic processing of pet feeding syringes mainly involves the sterilization of ethylene oxide and cobalt 60. The sterilization of ethylene oxide is mainly gas sterilization. Currently, medical devices are widely sterilized by ethylene oxide. Cobalt 60 sterilization is radiation sterilization, which is relatively costly. The main advantages of both are as follows:

Ethylene oxide sterilization for pet feeding syringe has several advantages:
1. Can kill all microorganisms, including bacterial spores.
2. Sterilized items can be wrapped, packaged in their entirety, and kept sterile before use.
3. Does not corrode plastic, metal and rubber;
4. Can penetrate irregular shapes products

The advantages of cobalt 60 sterilization for irradiation sterilization are:
1. The penetrating power is very strong, and it is not necessary to disassemble the product packaging during irradiation, which can ensure that all parts of the product are uniformly irradiated, and the sterilization effect can be achieved.
2. Irradiation sterilization is carried out under normal temperature and normal pressure, no residue, no pollution, no residue, convenient and fast.

The child resistant cap bottle with desiccant cap

The new design of the child proof bottle is based on safety and prevents people other than the patient from eating, especially in children and mental patients.
At present, ordinary packaging bottles are generally sealed by aluminum foil gaskets to ensure the sealing property, but after the gasket is opened, the sealing effect is not guaranteed, and the tablets and capsules are frequently opened in the bottle cap, and the sealing is not good. Will cause the drug to absorb water or oxidize. Therefore, relying mainly on gasket sealing, there are great hidden dangers. Secondly, when the cap is frequently opened, moisture will invade the bottle and accelerate the deterioration of the drug. In particular, such as aspirin, sodium phenobarbital, effervescent tablets, test strips, etc., are prone to deformation or deterioration after moisture absorption, and must be packaged in a bottle with good sealing properties.
Therefore, the special point of the special screw cap safety bottle is combined with the dual function of preventing moisture and opening, ensuring that the medicine remaining in the bottle after opening is still in a relatively sealed state during the use of the medicine; The risk of children accidentally opening and eating drugs.

The child resistant cap bottle with desiccant cap

how to test the sealing of packaging container(veterinary syringe) in UPS

how to test the sealing of packaging container(veterinary syringe) in UPS
The sealing of packaging container is a topic which is concerned by pharmaceutical workers,the traditional test methods have some cons,like
material wastage much,unidentified the leak level and so on.So many countries are being developed new test methods.The UPS 1207 of USA  put forward multiple test measures,such as pressure/vacuum decay, tracer gas detection,electrion process and laser method.
Then i will detailedly introduce the three major test methods,vacuum decay,Electrical Conductivity and Capacitance Test and Laser-based Gas Headspace Analysis.

1. vacuum decay,the theory of vacuum decay is that put packaging container in the special test chamber,vacuumize the chamber,the air of the packaging container will enter into the test chamber on account of inner and outer pressure difference,the pressure sensor will detect the pressure change,then compare the pressure changing value with reference value,then you can judge the packaging container whether qualified.The vacuum decay method is a nondestructive and quantitative assay (USP <1207.2>). It detects leaks in nonporous, rigid or flexible packages. Packages with a porous component can be tested by masking the porous package component (USP <1207.2>). The test sample is placed in a closely fitting evacuation test chamber, which is equipped with an external vacuum source (USP <1207.2>). The test chamber plus test system dead space are evacuated for a predetermined period of time (USP <1207.2>). The targeted vacuum level chosen for the test is predetermined on the basis of the test sample type under evaluation (USP <1207.2>). The rise in dead space pressure (i.e., vacuum decay) is monitored for a predetermined length of time using absolute and/or differential pressure transducers (USP <1207.2>). A pressure increase that exceeds a predetermined pass/fail limit established using negative controls indicates container leakage (USP <1207.2>).
2. Electrical Conductivity and Capacitance Test.The Electrical Conductivity and Capacitance Test is also known as High Voltage Leak Detection (HVLD). This assay looks for leaks in walls of nonporous, rigid or flexible packaging containing liquid or semi-liquid product (e.g. ampoules) (USP <1207.2> ). During the assay, a high voltage and high frequency charge is applied across the containerclosure system (White, 2012). A detected leak will cause an increase in current across the high voltage electrodes, triggering the reject mechanism for the leak detector (White, 2012). Key factors for the assay include the voltage level, probe positioning, the container-closure system geometry, the wall thickness, and the product formulation.
3. Laser-based Gas Headspace Analysis.According to detect the change of the pressure,water vapour and oxygen gas of gas headspace of packaging container,to judge the completeness of plastic bottles.The theory is that when the laser penetrate the gas headspace of packaging container,the water vapour and oxygen gas will absorb some laser,the laser absorptive amount is proportional to corresponding matter content.

What test methods can be choose to test the common packaging container.

1. syringe can choose the vacuum decay and electrical conductivity and capacitance test
2. vaccine bottle can choose the vacuum decay,electrical conductivity and capacitance test,Laser-based Gas Headspace Analysis
3. the eye dropper bottle can choose the vacuum decay and electrical conductivity and capacitance test
4. the effervescent tube can choose the vacuum decay and electrical conductivity and capacitance test

The new material vial - cyclo olefin polymer (cop) bottle

First,what is the COP material?
The cyclo olefin polymer (cop) material is a lightweight, breakage-resistant packaging for protein-based, peptide-based, floating particle, and high-viscosity drugs, this plastic material is suitable for use in prefilled syringes and vials where transparency, sterilization, breakage-resistance, and stability are important.
Second,The sterilization method of COP vial.
COP can be through steam-, ethylene oxide-, and gamma-sterilization without any significant change.
Third, the advantages of the COP material vial

As with most other packaged goods pharmaceuticals need reliable and speedy packaging solutions that deliver a combination of product protection, quality, tamper evidence, patient comfort and security needs. Constant innovations in the pharmaceuticals themselves (such as prefilled syringes, blow fill seal vials, powder applications and others) also have a direct impact on the pharmaceutical packaging.